A biodegradable, elastic patch to treat congenital diaphragmatic hernia


A College of Texas at Arlington bioengineering researcher is main a group to develop a biodegradable, elastic patch as a brand new therapy for congenital diaphragmatic hernia (CDH).

Considered one of each three newborns with this devastating situation dies. 5 youngsters are born with this delivery defect daily in america.

Yi Hong, a professor within the Division of Bioengineering, is collaborating with Aijun Wang and Dr. Diana L. Farmer from the College of California-Davis and Jun Liao, a UT Arlington affiliate professor of bioengineering, on the extremely aggressive $441,000 Nationwide Institutes of Well being grant.

We’re constructing one thing that provides and takes and grows with the kid. CDH is a severe delivery defect characterised by incomplete improvement of the diaphragm.”

Yi Hong, Professor, Division of Bioengineering, College of Texas at Arlington

Hong mentioned CDH can permit abdomen and intestines to maneuver into the chest cavity, which compresses the lungs and impairs improvement. Surgical procedure can generally restore the defect; in any other case, a prosthetic patch have to be used as a bridge. These patches are often made from artificial, biologically inactive supplies corresponding to Gore-Tex.

“When that is finished, these patches do not develop with the kid,” Hong mentioned. “Additionally, the kid typically experiences one other hernia. So creating a biodegradable, extra pure resolution is important for these youngsters’s survival.”

Michael Cho, professor and chair of the UTA Division of Bioengineering, mentioned this might be life-saving analysis.

“Dr. Hong’s analysis can assist so many sufferers,” Cho mentioned. “Taking the analysis from our labs and utilizing it within the medical subject with companions makes UTA’s analysis so private, so important for what this College represents. It additionally represents the division’s aim of driving translational and transformative analysis.”

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